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The Eugene area is a great place to explore Oregon wines. Within just a few miles of town you can visit many different wineries, with many different approaches to tasting room style and types of wines. Here is a good cross section of what's available:
You should plan on spending 5 to 8 hours on your tour, visiting about one winery per hour or so (don't rush to see as many places as you can cram into the day - you'll forget them all). Bring a lunch - there are many great places to enjoy a picnic along the way.
Don't forget - even tasting wine can impair your driving. So bring a designated driver or hire a driving service.