If you’re looking to wash your clothes this is a big problem in the Cesky Krumlov area. In the town itself there is only one laundrette which has irregular opening hours where you have to phone every day to find out whether they are open or not. They also may not answer the phone.
However, there is a self-service laundrette in Lipno Marina (3 machines and dryers).
This is a service that really needs to be considered if the local businesses wish to cater for tourists like they profess to.