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Mark Twain Brewing Company

₹₹ - ₹₹₹American, ,
422 N Main St, Hannibal, MO 63401-3324
+1 573-406-1300
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  • Excellent29%
  • Very good38%
  • Average20%
  • Poor8%
  • Terrible5%
Travellers talk about
“burger” (54 reviews)
“apricot wheat” (8 reviews)
“pulled pork” (29 reviews)
Open Now
11:30 AM - 11:00 PM Hours
American, Bar, Pub, Brew Pub
₹₹ - ₹₹₹
422 N Main St, Hannibal, MO 63401-3324
All Details
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JPMiles / Payback Arrow
JPMiles / Payback Arrow
Reviews (447)
Traveller rating
Traveller type
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1 - 10 of 445 reviews

Reviewed yesterday via mobile

We ended up there twice in one weekend! The food was fantastic.... highly recommend the burnt ends. Our service was great and must say that every beer we tried was awesome. Dont miss this place if you're in Hannibal!

Thank Stephanie M
Reviewed 3 days ago

This was our first lunch stop for our weekend. We chose to sit upstairs. Air conditioning was not available and got a bit warm. Sandwiches were delicious and portions were large. Enjoyed the beer flight we ordered. Overall nice experience.

Thank donnahulett
Reviewed 5 days ago via mobile

We came on a Sunday afternoon and were seated right away. We waited a long time for our food. The fish and chips was really greasy.

Thank Melissa B
Reviewed 1 week ago via mobile

We had a Groupon for this place. Thank God; because paying full price would’ve been an atrocity. My kids are fairly patient, but waiting 45 minutes for our food when the restaurant just opened for the day and was fairly empty had them anxious and...More

Thank had832018
Reviewed 1 week ago via mobile

Visiting family in Hannibal and we always stop at the dinette, cassano's, and Chocolate Stam. Now adding the brewery. Great beers on tap from them and others! Didn't eat, but watched everyone else get food and they all loved it. Young kid was bartender and...More

Thank Nicole S
Reviewed 1 week ago via mobile

Food was good, reasonable to high price and the view from the 2nd floor was nice, but the AC wasn't working.

Thank Laura G
Reviewed 1 week ago via mobile

I enjoyed the location and very comfortable with a great view upstairs. Food was less than inspiring with even lazier service. I would guess that the problem is that there was not a member of the wait staff over 20 and they seemed to think...More

Thank buytaerts
Reviewed 2 weeks ago via mobile

Good selection of craft beers available, had the flight of four which allowed me to sample their different brews. The Habenero Apricot was interesting, a little kick with each sip. Food was good and portions were large.

Thank shr54
Reviewed 2 weeks ago

Recently stopped here for lunch. The beer was good but the food was a big disappointment. The onion rings were almost burnt beyond being edible and the sandwich was also toasted bordering on being burnt. Our waitress was absent for most of our stay so...More

Thank Michael H
Reviewed 2 weeks ago via mobile

Great atmosphere, good food. Excellent service. Wide variety of food. Variety of beer. Reasonably priced menu.

Thank Jeanie12345
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Ask a question
Questions & Answers
1 August 2018|
AnswerShow all 2 answers
Response from HungryMom1 | Reviewed this property |
It looks to me like they are open Sundays. I would be surprised if they weren’t open September 2.
David F
19 April 2018|
AnswerShow all 7 answers
Response from Jason G | Property representative |
Yes, we have an extensive wine list and several local Missouri wines options as well. We have a full bar with a bourbon, scotch, and wine list.
Sierra H
24 September 2017|
AnswerShow all 7 answers
Response from whitesox18 | Reviewed this property |
I dont think so and saw no kids in there
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Restaurant Details

Rating summary
  • Food
  • Value
American, Bar, Pub, Brew Pub
Lunch, Dinner
Restaurant features
Takeout, Seating, Waitstaff, Parking Available, Television, Highchairs Available, Wheelchair Accessible, Serves Alcohol, Full Bar, Free Wifi, Outdoor Seating
Good for
Bar Scene, Special Occasion Dining, Groups, Local cuisine, Kids, Child-friendly
Open Hours
12:00 AM - 9:00 PM
11:30 AM - 10:30 PM
11:30 AM - 10:30 PM
11:30 AM - 10:30 PM
11:30 AM - 11:00 PM
11:00 AM - 12:00 AM
11:00 AM - 12:00 AM
Location and Contact Information
  • Address: 422 N Main St, Hannibal, MO 63401-3324
  • Location: United States  >  Missouri (MO)  >  Hannibal
  • Phone Number: +1 573-406-1300
  • E-mail
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