Vines, wines and the people who love them are central to the economy of Napa Valley. Other treats for the taste buds are in store, too, in the form of local olive oils, tomatoes, cheeses and mustard. The other senses are catered for with a vibrant visual arts scene. Hire a car or book a taxi or limousine to travel safely between sights. The Napa Valley Wine Train offers an unusual way to experience the views and vintages. A relaxing array of spas and mud baths and the Old Faithful geyser are attractions in Calistoga.

Everyone knows Aspen as a top-notch winter resort town. But outdoor enthusiasts will enjoy it in the summer, too, when the mountains become a perfect setting for hiking, biking and horseback tours. Some may be surprised to find it’s a top romance destination—but after all that outdoor exercise, who wouldn’t want to repair to a luxurious hotel room or a cozy, firelit bar?

Stretching 126 miles south towards Cuba, the stunning Keys are a perfect escape. Highlights along the way include Key Largo, Islamorada, Marathon, Big Pine Key and the irrepressible Key West. Come face to face with an amazing array of fish while snorkelling, diving or fishing in the warm turquoise waters. Creeks, coral and costumed shows are other lures along the way. Highway 1 is a spectacular ribbon tying together the islands and atolls of this paradise between the Gulf of Mexico and the Atlantic.

There are no two identical Bahamas holidays. With options as diverse as its 700 islands, the Bahamas may seem schizophrenic: is it a family destination, a place for lovers to sneak away, a gambling mecca, a cruise-afficianado’s chief port of call or a shopper’s world market? The answer is, yes. It’s that, too.

U.S. citizens still need to jump through a few hoops to visit Cuba, but as visitors from around the world know, this island offers some amazing opportunities for cultural exchange. Havana is a mix of old-world architecture and of-the-moment culture. Head out of the capital city to the small town of Trinidad to see more Spanish colonial architecture. It’s a UNESCO World Heritage Site and a fantastic home base for a visit to the Valley of the Sugar Mills, a pocket of land that formerly served as the centre of Cuba’s sugar industry.

Jamaica is a melting pot of African, Asian, European and Middle Eastern cultures. You'll experience this diversity in its strong crafts tradition, performing arts and distinctive dining options, like ackee and saltfish with roast breadfruit. Take your holiday to new heights at famed cliff jumping spot, Negril Cliffs. Jamaica offers long beaches, protected coves, rugged mountains, waterfalls, caves and sunshine and chances to play in the surf, ride horses and swim with dolphins. Jump in!

More than 60 idyllic islands, including Jost Van Dyke, Tortola, Anegada and Virgin Gorda, make up the BVI. Turquoise waters offer thrilling diving, fishing, sailing and swimming. Tortola is the largest island in the volcanic chain and has beautiful beaches and coves, forts, ruins and warm, welcoming people. Virgin Gorda boasts yacht clubs, chic resorts and secluded sands. Coconut palms shade beaches on tiny Jost van Dyke. Sailing is a popular way to travel between islands. Ferries are the other option.

Antigua has hundreds of beaches, from the bustling Pigeon Point to the kitesurfing paradise of Jabberwock Beach. It's fun to mix it up—a day spent in a secluded cove, another spent people-watching at a tourist magnet. When you’re tired of sun and sand you can shoot ‘em up at Reservoir Range, where archery and air pistols are a fun way to work out any lingering pre-holiday stress. A tour of the Antigua Distillery is a spirited way to experience a true taste of the island.

There's more than one way to enjoy the spa experience in St. Lucia. One is to book a treatment at any of the luxury spas or resorts on the island. The other is to visit Sulphur Springs, inside the bowl of an extinct volcano, where you're welcome to try a volcanic mud bath or the 31°C/88°F Roman bath.

The relatively small island of Bora Bora is an activity giant, offering visitors the chance to experience a 4x4 safari, sunbathe and swim at white sandy beaches, dive in a natural underwater park among fish and corals, experience thrilling shark feedings, or circle the turquoise lagoon by boat. And Bora Bora is a superlative romantic spot. Fall captive to this lush gem of a Polynesian island by sharing an intimate midnight dinner on the beach; visiting the Lagoonarium, the Diving Centre, the Coral Gardens or the Leopard Rays Trench; or taking it all in from the lofty heights of 2,300-foot Mount Otemanu.