Vines, wines and the people who love them are central to the economy of Napa Valley. Other treats for the taste buds are in store, too, in the form of local olive oils, tomatoes, cheeses and mustard. The other senses are catered for with a vibrant visual arts scene. Hire a car or book a taxi or limousine to travel safely between sights. The Napa Valley Wine Train offers an unusual way to experience the views and vintages. A relaxing array of spas and mud baths and the Old Faithful geyser are attractions in Calistoga.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

If you’re a history buff and a die-hard foodie, Chicago’s your kind of town. Take an architectural-history walking tour, then dine at Alinea (the most celebrated molecular-gastronomy restaurant in the U.S.). And don’t miss the Museum of Science and Industry, the biggest science museum in the Western Hemisphere.

Atlanta has been dubbed everything from the "capital of the new South" and "the next international city" to "the best place to do business." It's also a great place to visit. Fueled by the prosperity of local mega companies like Coca Cola and Holiday Inn, the prestige of hosting the 1996 Summer Olympic Games and the energy of young upwardly mobile types who have migrated to the city in droves - Atlanta is on fire. And this time it's a good thing. From world-class restaurants and a myriad of cultural attractions to a hip nightlife and sporting events galore, the city is cosmopolitan in every sense of the word. But Atlanta has also managed to maintain its historic character. Stop by the Atlanta History Centre or visit the Martin Luther King Jr. Historical Site, a moving tribute to an American icon. Browse through the former home of famous author Margaret Mitchell or pop into the Jimmy Carter Library and Museum for details on the life and times of the former president and his family. Whether you choose modern urban endeavors or old southern pleasures, Atlanta will not disappoint.

From the National Mall’s monuments and memorials to vibrant neighbourhoods filled with character and charm, DC is a world-class destination featuring breathtaking views, award-winning hotels and hundreds of free things to do. Experience outstanding performing arts at acclaimed theatres, shop in historic Georgetown, hear great live music at legendary venues, enjoy sporting entertainment from six professional franchises and be dazzled by a flourishing dining scene with Michelin-starred restaurants.

The first time you go to New York, go ahead and be a sight-seer—everyone should visit the Statue of Liberty, the Met, Times Square, etc. But on a return trip, pick a neighbourhood and go deep. You’ll find hole-in-the-wall bars, great delis, quirky shops… exploring the non-touristy side of New York is an incredibly rewarding experience for a traveller.

Atlantic City draws tourists by the car- and bus-load, topping more than 20 million visitors per year! Stroll along the famous Boardwalk with its numerous amusements and eateries or visit the historic Absecon Lighthouse and the new Wheel at Steel Pier. Several championship golf courses are within a 30 minute drive to attract golf enthusiasts. In summer, the local free beaches are popular with families. Beach bars are peppered throughout the resort and you can dig your toes in the sand and enjoy your favourite cocktails. Water-based activities include parasailing, charter fishing and dolphin-watching cruises. Casino hoppers have 9 establishments to choose from and there is something for everyone's taste. Those who remember Atlantic City in its pre-gambling days can wax nostalgic with a taste of saltwater taffy and iconic rolling chairs which have been Atlantic City favourites for over 100 years.

Saint Augustine is a luxurious, romantic holiday spot—you’ll find classic hotels and intimate restaurants. Those can be a dime a dozen, though. What sets Saint Augustine apart is its history—it’s the oldest European settlement in the U.S. And nowhere else in the world can you taste the waters of the Fountain of Youth archaeological Park (where Ponce de Leon may have landed). Who knows, if you holiday here, maybe you won’t need that Botox!

From quaint town shops and quiet beaches, to honky tonk arcades and carousels, the York area is guaranteed to entertain the whole family. Old York, run by the local historical society, contains nine different restored buildings, including "The Old Gaol," the oldest jail in America. The beautiful coastline provides cliff walks with views of an authentic Maine lighthouse. Head to nearby York Beach and visit York's Wild Kingdom, an amusement park and zoo that is home to Rewa, a White Bengal tiger.