Who cares about a little fog (okay, a lot of fog) when there’s so much to do in San Francisco? By day, explore Fisherman’s Wharf and the Aquarium of the Bay, ride a cable car, and stroll around the Presidio; by night, have a fabulous dinner (at a Michelin-starred restaurant or a tiny place in Chinatown), then hit some of the best clubs on the West Coast.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

North America's biggest and most popular ski resort, Vail is an alpine village in the heart of the Rocky Mountains. Long a favourite of serious skiers and jet setting celebrities, Vail now also draws a younger, hipper snowboarding crowd. Skiing is king at Vail Mountain and the Blue Sky Basin, but the area's vast splendor is perfect for hiking, biking, snowmobiling or scenery-gazing at any time of the year.

Mexico's fastest-growing resort area offers miles of empty desert and deserted beaches. Laid-back nightlife and old-fashioned fun in the sun is the Cabos' lure. Only certain beaches are safe for swimming, however, including Lovers' Beach and the more tempestuous and aptly named Divorce Beach. Whale-watching, hang-gliding, snorkelling, antique-hunting, golf and fishing, Loreto's historic mission, and sport fishing and dining in capital La Paz are other attractions. SuburBaja buses travel the coast.

You'll find crashing waves off Cabo's Pacific coast and sheltered, calm water on the Sea of Cortez. Given those options, Cabo has built a rare reputation for both excellent outdoor sports (big-game fishing, diving and kayaking, among others) and pure beach relaxation. Of course, there's also great nightlife. Cabo’s resorts, hotels and inns cater to everyone from honeymooners to families to Hollywood stars seeking a weekend getaway.

The first time you go to New York, go ahead and be a sight-seer—everyone should visit the Statue of Liberty, the Met, Times Square, etc. But on a return trip, pick a neighbourhood and go deep. You’ll find hole-in-the-wall bars, great delis, quirky shops… exploring the non-touristy side of New York is an incredibly rewarding experience for a traveller.

Ecologically diverse and sparsely populated, the Big Island of Hawaii is larger than all the other better-known Hawaiian islands combined. Rental cars allow visitors to discover wonders from snow-capped mountains to rainforests to deserts. Best known for Hawaii Volcanoes National Park, home to the longest volcanic eruption in recorded history, the Big Island caters both to those who crave adventure and to those looking for luxury, with the flotilla of decadent mega-resorts dotted along Kohala Coast.

It’s not just for spring-breakers. Cancun, with its golden beaches and perfect climate, is the premiere coastal destination in Mexico. And while there is certainly a 365-day party available for college students, resorts cater well to families and to those seeking solitude. This Yucatan paradise is also the gateway to the ruins of Tulum and Chichén Itzá.

There are no two identical Bahamas holidays. With options as diverse as its 700 islands, the Bahamas may seem schizophrenic: is it a family destination, a place for lovers to sneak away, a gambling mecca, a cruise-afficianado’s chief port of call or a shopper’s world market? The answer is, yes. It’s that, too.