Who cares about a little fog (okay, a lot of fog) when there’s so much to do in San Francisco? By day, explore Fisherman’s Wharf and the Aquarium of the Bay, ride a cable car, and stroll around the Presidio; by night, have a fabulous dinner (at a Michelin-starred restaurant or a tiny place in Chinatown), then hit some of the best clubs on the West Coast.

Modern myth has it that these days everyone in Los Angeles has written a screenplay, is writing a screenplay or is just visiting. For those in the latter category we offer a road map of ideas to help make a trip to this ultra-hip, ultra-happening haven easy, fun and exciting. While LA will always be associated with movies and movie stars, it is also a culturally vibrant city that boasts a range of interesting attractions from prestigious art museums and galleries to fabulous theatre, both well-known productions and smaller fringe shows. Art enthusiasts will be stunned by the extensive collections at the J. Paul Getty Center and the Los Angeles County Museum of Art. Visit the La Brea Tar Pits on Museum Row, then investigate the trendy shops on Melrose Avenue. Families will not want to miss the zoo or the action at Universal Studios Hollywood. Of course, no trip to LA would be complete without a stop at the Venice Beach Boardwalk or a visit to Mann's Chinese Theater and the Walk of Fame.

Seattle's petite downtown area and many attractions make it possible to pack a week’s experience into a weekend. Grab a latte and start at the world-famous Pike Place Market. Watch the fish fly and then head to the Space Needle for a dramatic view of the city and its surrounding waters. Return to earth and jump aboard a moonlit dinner cruise to Blake Island or canoe through the arbouretum.

What happens when a "gassy" Englishman rows into town feeling thirsty? A pub is born. And from that a city—in this case Vancouver. Though the pubs are plentiful, food and drink aren’t the only things to take in during your trip. In its 150 years, Vancouver has grown into a cosmopolitan city nestled in the great outdoors. Enjoy the snow-capped mountains, waterfront forests, cityside beaches, Olympic history and the world’s highest suspension bridge. Hipsters welcome. (Don’t worry, they don’t bite.)

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

If you’re a history buff and a die-hard foodie, Chicago’s your kind of town. Take an architectural-history walking tour, then dine at Alinea (the most celebrated molecular-gastronomy restaurant in the U.S.). And don’t miss the Museum of Science and Industry, the biggest science museum in the Western Hemisphere.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

Whether you're into sport, sunshine or salsa, Miami sizzles all year round with exciting entertainment venues and attractions, world-class hotels and restaurants, great beaches and a nightlife that never sleeps. While South Beach, with its hip nightclubs and pastel-hued buildings, gets all the press, other sections of Miami are just as hot and offer culture, recreation and more. Spend the day soaking in the sights and sounds of Little Havana or soaking up the rays at Haulover Beach Park. Explore the Art Deco District or take the children to the zoo. At the end of the day, chill out at one of the area's bars and nightclubs. In Miami at night, the day is just beginning.

From the National Mall’s monuments and memorials to vibrant neighbourhoods filled with character and charm, DC is a world-class destination featuring breathtaking views, award-winning hotels and hundreds of free things to do. Experience outstanding performing arts at acclaimed theatres, shop in historic Georgetown, hear great live music at legendary venues, enjoy sporting entertainment from six professional franchises and be dazzled by a flourishing dining scene with Michelin-starred restaurants.