In Peru's second-most populous city, aka "The White City," stunning colonial buildings made of pearly sillar stone vie for attention with the surrounding volcanoes and snow-capped peaks of the western Andes. Founded in 1540, it's a smorgasbord of mansions and museums. The top attraction, 215,000-square-foot Santa Catalina Monastery, is like its own city within a city, complete with fountains and cobblestone streets. Arequipa is the favorite base for visiting Colca Canyon and its massive condors.

Once infamous for dangerous gangs and drug activity, Medellin has been transformed. It’s now a vibrant destination for travelers seeking a culturally rich vacation. Medellin rises proudly from the belly of the Aburrá Valley, and its natural beauty makes a perfect setting for hiking, zip lining and horseback riding. Travel through lush jungle to Piedra de Penol, then climb the 740 steps to the top—a journey within a journey that rewards you with unforgettable views.

U.S. citizens still need to jump through a few hoops to visit Cuba, but as visitors from around the world know, this island offers some amazing opportunities for cultural exchange. Havana is a mix of old-world architecture and of-the-moment culture. Head out of the capital city to the small town of Trinidad to see more Spanish colonial architecture. It’s a UNESCO World Heritage Site and a fantastic home base for a visit to the Valley of the Sugar Mills, a pocket of land that formerly served as the centre of Cuba’s sugar industry.

Six islands in the Florida Keys comprise the village of Islamorada, known for its prime sport fishing. Rent a boat or participate in a guided tour to fish, snorkel, or swim with marine life. Fresh seafood is the hallmark of the Islamorada dining scene. Visit a tropical-themed bar to soak in the full Florida Keys experience with a frozen umbrella drink. For a dose of culture, take in fine art and music while strolling through the Morada Way Art and Cultural District.

Located at the northern end of the Daytona Beach area, Ormond Beach is an exceptional family holiday destination known for its beautiful natural beach, parks and gardens, scenic loop, elegant homes, historical landmarks, and cultural offerings. Travellers enjoy the small-town feel of its downtown shopping and arts area on Granada Boulevard – as well as its eclectic eateries – while a visit to Tomoka State Park (located along the river) is a great outing for kids and adults alike.