Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Known as the home of “the happiest place on Earth,” there’s more to Anaheim than thrilling theme parks. Bring your appetite to the Anaheim Packing District and Centre Street Promenade for some eclectic eateries and award-winning craft breweries. Explore the latest exhibits at the Muzeo Museum and Cultural Centre. Enjoy live music at the all-new House of Blues, now at the Anaheim GardenWalk.

Modern myth has it that these days everyone in Los Angeles has written a screenplay, is writing a screenplay or is just visiting. For those in the latter category we offer a road map of ideas to help make a trip to this ultra-hip, ultra-happening haven easy, fun and exciting. While LA will always be associated with movies and movie stars, it is also a culturally vibrant city that boasts a range of interesting attractions from prestigious art museums and galleries to fabulous theatre, both well-known productions and smaller fringe shows. Art enthusiasts will be stunned by the extensive collections at the J. Paul Getty Center and the Los Angeles County Museum of Art. Visit the La Brea Tar Pits on Museum Row, then investigate the trendy shops on Melrose Avenue. Families will not want to miss the zoo or the action at Universal Studios Hollywood. Of course, no trip to LA would be complete without a stop at the Venice Beach Boardwalk or a visit to Mann's Chinese Theater and the Walk of Fame.

A popular spot for getting wowed or soaked amid natural splendor, Niagara Falls attracts curious spectators and adventurous honeymooners from around the world. The splendid main attraction - more than six million feet of water cascading over a rocky crest - sits partially in the United States and partially in Canada. The U.S. side has recently been busy promoting other activities to lure visitors. Venues like the Aquarium of Niagara offer parents fun and engaging alternatives for kids, after or in between visits to the Falls. Outdoor recreation such as hiking, biking, fishing and camping can be found at the Niagara Falls State Park. The storied history of attempts to conquer the majestic Falls is captured at the Daredevil Museum; the Schoellkopf Museum concentrates on the history and geology. There's more to the Falls than, well, the Falls, including a wide array of dining and lodging options, from budget to upscale. This awe-inspiring region makes for an exhilarating and multi-faceted getaway

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Whether you're into sport, sunshine or salsa, Miami sizzles all year round with exciting entertainment venues and attractions, world-class hotels and restaurants, great beaches and a nightlife that never sleeps. While South Beach, with its hip nightclubs and pastel-hued buildings, gets all the press, other sections of Miami are just as hot and offer culture, recreation and more. Spend the day soaking in the sights and sounds of Little Havana or soaking up the rays at Haulover Beach Park. Explore the Art Deco District or take the children to the zoo. At the end of the day, chill out at one of the area's bars and nightclubs. In Miami at night, the day is just beginning.

Known as New York's tough neighbour with a major international airport, Newark is a destination in its own right. The city is undergoing revitalisation efforts and its attractions include several large parks, art galleries and architecturally significant buildings. The Newark Museum is a complex of art and science exhibits, a mini-zoo, a planetarium and more. Theatre, music and dance performances take place at venues such as the New Jersey Performing Arts Center and Newark Symphony Hall.

Montreal, c’est si bon! This French-speaking city is considered the cultural capital of Canada, and is a cosmopolitan celebration of Québécois style. A horse-drawn carriage ride around the cobblestone streets and grand buildings of Vieux-Montréal will give you a taste of European flavour. The Basilique Notre-Dame is a confection of stained glass, and the Plateau Mont-Royal district will delight you with its quaint boutiques and cafés. Dig in to a massive plate of poutine to fuel up for a tour of the epic Olympic Park.

You've got to walk the Freedom Trail the first time you visit Boston. That's just a given. Make sure you step off the line on the pavement, though, and explore some of Boston's fine museums (try the Gardner—art masterpieces displayed in their collector's mansion) and old neighbourhoods (like the North End, where you can get the best cannoli this side of Italy). You can't claim to have experienced real Boston culture, though, unless you've watched a Red Sox game from the bleachers.