We stayed only for 3 nights in Rhodes and every second was perfect because of the place we stayed. The lady that runs it was so friendly
In the first moments of arrival, Luisa began serving us. She wellcomed us warmly when we arrived from the ferry and offered us one cold drink, making us feel at home.
Since we had booked the rooms only 2 weeks before (Even in high season), we didn't expect too much. A good stay for the price we paid, rooms were clean.
The location is in the heart of the Old City. Very close to everywhere!!
Do not expect much from the rooms. Isole is not a hotel, but also here is not a pension. It is like a house of yours. The blue windows, white high ceilings..Everything was perfect, but i should say that the best is the dialog of Luisa and Guido with the customers. This is called friendship.

I stayed for just one night and I wish I'd had longer. Louisa is such a fantastic, worldly, genuinely interested women I've ever met. The hotel is in a great location in the old town but as cabs can't drive you there you have to carry your luggage. Worth it to me though, to be in an oasis in the heart of the old city. I had a small room but with just 1 person I didn't need any more room. More importantly the room was very clean. Great value, a fun, interesting environment and ten out of ten for Louisa. A real pleasure.

I stayed at the Hotel Isole for a night last month (July 2010). The city is very crowded in the summer but the hotel was quiet and calm, despite being ideally located just off the main shopping street. It's tucked away around a corner down a narrow alley, and the room felt like a little hideaway. The owners were very welcoming and the hotel is a great value. I'd recommend any solo traveler, or couple on a budget, to base yourself here and enjoy exploring Rhodes.
Everything is small, like all of medieval Rhodes, but clean, well kept, and with a good shower. Decor is basic but again clean and very sufficient.

Hotel Isola was a welcoming place to find in the heart of Old City Rhodes. Although Rhodes was cool and pre-season for activity, the operators, Guido and Luisa were warm, welcoming and helpful. We were directed to a REAL Greek family restaurant "Meyiotov" and a delightful afternoon music bar "Mupobohies" and provided with information about sites and stops around the island. Everything... the cheerful blue decor, extenive travel books + extra novels, unique rooms including a roof terrace, resident cat, happy hour at the bar, interactive owners.... made up for a great stay. We were only a little letdown by the Greek breakfast that didn't live up to our Turkish experiences. An enjoyable spot and interesting city to explore.