If you're using public transportation, this location can't be beat. The city trolley runs right behind the hotel and is easy to get to. It is also about a block from the Gaslamp area, where there are many restaurants to choose from. The service at the Omni was good, too. Our room was on the 15th floor, facing the water. We did not hear the trains that others had mentioned. We liked our little balcony, and the view of the bridge/water was nice. The room was clean and the bed and pillows were comfortable. However, the walls were a bit thin. Our first night (and morning) we were entertained by the lovers next door; the second night we were subjected to a party seemingly comprised of chatty, loud 20-year-olds. In a building this new, it is surprising that the soundproofing is not better. Since we stayed over a weekend, I would assume this is not as much of an issue during the week. If you stay here, I recommend you do so alone. The bathroom has louvers on the door and in between the bathroom and the main room. While this may be helpful in dissipating steam, it also means that you can hear EVERYTHING the bathroom occupant is doing. There was also a jackhammer-type noise every time anyone used the shower. You could hear the noise coming from other rooms as well. The hallway was strangely loud, too.

If I needed a place to stay on business during the week, I would most likely return to the Omni. If I was going to be in SD over the weekend, however, I would try somewhere else.