When traveling to Binghamton, there are two choices for Hampton Inn's - this one (in Vestal) and the one right in Binghamton. Stay at this one. True it is an older Hampton Inn, but it is neat and clean, and rooms have updated furniture and are decent sized. Area around hotel is OK, and not city-like. If you have some free time, check out the carousels in the area.
One unusual item: When we checked in we found a "towel creature" in the bathroom. On cruises we have often found towel animals (fish, octopus, etc.) folded up on the bed. Hampton Inn seems to be test driving this idea; only in this case it was a somewhat creepy looking baby/bat looking thing hanging in the bathroom. It creeped the kids out so I took it down. See the photo.
This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC