We stayed here for one night during a tour of the Mekong Delta (with the amazing Jason Superstar! - see the forums, he is best person to do a private tour). I was pleasantly surprised at how clean and large (with 3 adults) our room on the 9th floor was. The free breakfast was great, and though we didn't eat there, the rooftop bar had excellent views. I can't say much about the staff since Jason orchestrated most things beforehand, but the spa is worth considering. You'll probably pay a little more than at the average place on the street ($12 for an hour long body massage and 30 min reflexology) but it's on the 10th floor so it's quiet and is still reasonably priced, particularly since it actually has a "spa" feel.
Another reviewer mentioned that it was a good choice, but not posh and that is a spot on description. The Victoria seems to be the luxe hotel in Can Tho, but if you are only staying one night and busy with activities around the Mekong - spend a third of the price and stay at this great option. For one night - we had no regrets and were thrilled with the bill!
Room Tip: A higher floor provides great views of the city and river!
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This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC