If you like highways and motels, then by all means. However, City Inn Hotel is certainly not luxe by any stretch of the imagination. The money that my mother and I had intended to save ended up being used to hire taxis to take us back to the hotel at night, since there is no train station nearby and the buses are extremely erratic, running on what appears to be a nonexistent timetable.
As a result of food poisoning, my mother was confined to the hotel room for one of three days for which we were in Antwerp, leaving her to grapple with filthy surrounds, a shower that wouldn't work as well as a rock-hard bed. Service was cold and unhelpful and the nicest person there was the housekeeper who appeared sympathetic when I told her about my mother's predicament. If I have to say anything positive about this hotel, it would be that it was ridiculously easy for my Dutch friend to come and pick me up to go to Breda for the day. That's about it, really.
For the three days I had accommodation in Antwerp, I only spent one day exploring the city (the other two days were spent in Breda and Luxembourg respectively). City Inn was no doubt a contributing factor.