We stayed for only one night in this stylish hotel. The staff were extremely helpful, including recommending a great restaurant for lunch, the location was excellent, and the room was stylish yet workable. I will definitely stay here on my next trip to Milan!

To call such a nondescript and bleak building a Palazzo is a new level of hype!
We spent 2 nights in the hotel last weekend in room 15. The room itself together with the bathroom could be an example of what's wrong in Italy. Everything looked beautifully, lots of style but little practical substance. It took 30 minutes to get warm water on Sunday morning, the mini bar did not work.
The room was so small that there was no space for a table.
We had a twin (!) shower but no door for the toilet.
Breakfast is served till 10h30, which sounds good. When we arrived at 10h15, the buffet was nearly empty and when we indicated that there was no more cheese available, it was politely acknowledged, but not changed.
On the positive side, the location is great and the staff was extremely friendly and helpfull.
And Wifi is free, very good.
Of course you can only judge a hotel from your own experience, which in our case is room 15.
But I believe the hotel is better than just this room and that's why they get 3 stars.

I recently spent 2 nights at the Palazzo Segreti. Overall it was a decent stay and reasonably priced.

Highs:
- Good location
- Stylish
- Excellent service; all the staff were very nice and helpful
- Good value
- Comfortable bed
- Fast and free WiFi
- No charge for the local and free calls I made (0800 numbers)

Lows:
- I might chalk this up to user error or arriving in the dark but it was difficult to find. The door is small and marked only by a small sign so I was walking up and down the street looking for a hotel entrance when I arrived at #8 and it appeared to be the entrance to an apartment building. Eventually I found it.
- No desk in my room; normally not a big deal but on this trip I needed to work and so was forced to work sitting on my bed
- The lighting in the room was pretty terrible. Whole corners of the room were just dark regardless of how high I had the lights on. In fact the whole hotel had bad lighting.
- The satellite TV kept cutting in and out (perhaps a function of the wind and rain)
- The breakfast was fine but no hot items offered

Very nice hotel & fantastic location : 20 meters from Via Dante (but also very quiet as it's in a small street) and Milan's main attractions are in a walking distance. Our stay was perfect there. The staff is excellent : they managed to get us tickets for the Cenacolo Vinciano even if all prebookings were closed. We loved our room (the 11). We loved the place (old palace, modern design). The only little minus is the place to park the car: it's very close to the hotel but quite expensive (as all parkings in Milan are). The hotel should negotiate some kind of arrangements for its clients to have a discount there. We would definitly recommend this hotel. Palazzo Segretti opened in 2011 and I'm sure it will become very soon one of the travellers' favorite!