Stayed here for 4 nights in September for b/f birthday. After reading reviews on here, did not know what to expect but was very pleasantly surprised! The check in was easy. Room was great if a bit little but how much room do you need? Great shower, lovely staff. We did not ever wake up early enough for the brekkie but it looked substantial - cereals, toast, juice, coffee etc.
The location was fine - need to take a bus or metro into the centre of Rome(good thing about being near to Termini was that buses ran thru the night so no need to pay for cabs late into the night) but the journeys were only about 20 mins max so no hardship whatsoever.
Cab to and from airport was €60 each way - you can organise a coach shuttle from nr the termini for about €9 but we had a fairly early flight home and a cab was easier.
Venture into Trastavere for great food / drinks. Do take the walking tours of the Colosseo and ancient forums.

I booked a single at the Midi Hotel through Lastminute, at €50/night, and I have to say it was a very decent accomodation and extremely good value too.

The room on the first floor looking the nice roman patio value was clean, and the attention of reception was correct.
The breakfast was nice too although the coffee was instant.

On the possible negative sides:
- a previous review stated that they had an issue with water leaking from the last floor that they are building on top of the building. Well they don't seem to have completed the works, so that might be a cause of trouble

- to enter the hotel you need to ring a bell and the receptionist will open the door from their desk. On my first night a guest was ringing that bell at least for half an hour before someone appeared.

- the reception staff changed many times throughout my stay, at least four or five different people attended me during my three night stay, which seems far too many for a 10 room hotel.

- the hotel next door "Hotel Center" seems to share the reception with the Midi, in fact their customers plus other Hotel's customers on the other side of the patio had breakfast at the Midi, all comunicatiing through the Patio. Although it didn't mean anything wrong to me, I think It poses some security issues.

I read the reviews on this side and was surprised when I went to the Midi Hotel. From the outside it looked a bit shabby but inside it's beautiful. The whole place is redecorated. The rooms are no very big but they got the cleanest bath rooms I've ever seen in a hotel. Well, the breakfast (like everywhere in Italy) is not a real breakfast.
I can say I liked staying at the Midi Hotel also because its good place near the station.

We were able to check in early at 11am to our comfortable, clean, modern room. Everything worked. Quiet, with a balcony, but we were at the back and if tram noise upsets you the front rooms might be a problem. Shower had fixed overhead head and hand unit too. Plenty of hot water.
Staff were friendly and helpful.
Location was fine once you worked out how to get to Termini station/bus station using the underground conveyor that goes the length of the station. Not the most central location, but good for the price, and felt quite safe to us.
Breakfast was mediocre, but at least you could start the day with juice and coffee.
In summary, very good value. Not ideal if you're old or infirm, but that probably goes for Rome in general.