Very good location. Right next to termini and there was a market every day right on our door step. Very touristy area.
Service was terrible in some cases. We waited for a VERY long time before being allowed into our room. We had to change rooms TWICE!
Room quality- AMAZING!!
plasma tv, fridge, splendid air conditioning, 5 room was very spacious! very clean!
we also had a POWERCUT !!!
Value for the money we paid! Quite good!

Easy to find near the main train station. Excellent location, but difficult to find reception. Eventually we ended up over the road at Hotel Hollywood. Room was nice and big with nice view of the courtyard and street from the window. In the morning breakfast was available in a common kitchen area, and with only 2 chairs it became a waiting game to get in before the next room got in there.

I stayed 3 nights at Sergio House.
First impression was very positive: hotel owner was kind and friendly, room and bathroom clean. But at the end of my stay I also found negative aspect.
I will try summarize the good and the bad:

Good
- position: 100 mt from Termini rail station (wich is also the main bus stop and metro station in Rome)
- price: payed 70 eu/night for a double, cheaper than similar accomodations
- kitchen availability: freely usable, equipped with burner and fridge
- courtesy: all the personnel was cordial and helpful

Bad
- room tidying up: in 3 days no one ever cleaned the room, nor made the beds
- light leak: since the hotel is located at the ground floor and the quarter is not so safe, window-shutter are permanently closed (locked with a chain!), so don't exepect a bright place
- noise: maybe because of thin walls/door, but in the morning I never waked up by myself: I was "helped" by room neighbours
- shower: as I wrote, (the two) toilets are clean, but only one has the shower and it's a basis-free one: water falls straight on the floor (and on the toilet seat)
- luggage: if you will need, as I did, to leave luggage for some hours, you will have to pay 5 non-negotiable euros for each piece. This is not my first stay in a hotel in Rome, but it's the first time I have to pay for this kind of favour

My overall rating is 3; advice is to choose it if looking for something cheap and well located as a starting point to visit Rome, but not for a relaxing vacation.