Admittedly, the hotel is quite outside from the center of Rome and must be a pain to get there by taxi and busses, as the latter are indeed not very reliable. However, there is a train station very close to the hotel, via which it's very simple and cheap to get to the center.
The price of the triple room was very reasonable and actually lower than expected. The breakfast room as well as a little kitchen was accessible 24/7. So you could always have a tea during the day. The breakfast itself wasn't of high quality, e.g. there wasn't any sausage (but that's just the German in me speaking;), but satisfactory.
The atmosphere was nice and the family/staff very helpful and pleasant. Basic conversation in English was absolutely possible.
If you plan to spend most of the time downtown of Rome and not have to go back to the hotel several times during the day, Villa Rome is a very good option to consider.

The house is located at a distance of one minute walk from the railroad-metropolitan station Ottavia, and it is quiet because is protected from the street noise with a brick wall. There is an open water pool for guests.
The food was much better than I had at other B&B places, it included a big variety of ripe fruits - it was November; the guests are allowed to use the kitchen with a gas stove, many pans, dishes, spices, cooking oil.
The hosts were very friendly, were always ready to help, even they made phone calls because I do not speak Italian. They even allowed to use their computer to check and send E-mail. Later I discovered that across the street from their house you can use Internet, telephone and even Skype at a very low price of less than a euro for half an hour - the cheapest service that I found in Rome, and I did not find Skype available at other places.

Villa Rome is a very nice big house with nice little rooms including bathrooms, a wide and friendly room for a tasty and big brekfast with a big kitchen, where you can prepare your own meal. outside there is a swimming pool where you can cool down and relax. The owners Isabella and Paolo are very nice and friendly people who help you out with information if necessary and keep the place clean. The house is in a calm area and easily reached by train and later at night by night bus. I love this house and their owners very much so I will visit Villa Rome for the third time this year

The family told us their B&B was really close to the center of Rome. Not so...., we had to take a taxi in the end, because the bus connection was really bad.
When we came there, the room was dirty and it didn't look at all it had looked at the photos we had seen. Next morning we went for breakfast and the bread was moldy.... Couldn't wait to get away the next day.