This is my 5th night at Anthony's B&B and I'm more than happy with it. Spacious, clean rooms with ensuite, just around the block from a grocery store and two blocks from Castro Pretoria metro stop. About a 10 minute walk to Termini, the farthest you'd probably want to schlep your luggage around. Located on the 5th floor of an apartment building that seems to house offices as well, Anthony's was quiet and practical. Breakfast was decent (yogurt, fruit, pastries, boiled eggs, cereal, juice, cappuccino / espresso) and wifi was good.
While there's not much to do in the area, I didn't mind staying near Termini as it gave me more options for buses. There is a laundry nearby (€10 per load) and you pick up in an hour.
Travel tips: (1) There is a separate line at the Coliseum for Roma Pass holders, another benefit of having the pass – skipping the long lines waiting to buy tickets. The usual entrance fee is €12 and is easily the most expensive of all attractions on the Roma Pass, so make sure the Coliseum is either your first or second stop. (2) Online forums have been reporting that the Roma Pass is becoming difficult to get, with quantities running out quickly. They’re sold at all the tourist information kiosks spread across the city and at some convenience / tobacco stores. Try and get one early in your trip as the museums / attractions it includes is extensive. (3) Rick Steves has free downloadable walking tours of various sites in Rome, including Ostia Antica and the Coliseum. I found these informative and entertaining. (4) There are lots of buses waiting to take passengers from the airport to Termini, the main train/bus station. I noticed three different companies, prices ranging from €4-8, for seemingly the same service. (5) If coming from Termini, drag your luggage on the side of the street instead of on the very bumpy sidewalks. Don't worry. Everyone does it!
For more tips on what to do in Rome, including an easy daytrip to Ostia Antica, check out my round-the-world blog:
http://dreamtravelblog.wordpress.com/2011/11/06/rome-by-numbers/
Room Tip: There is a temperature panel in the room but I didn't see an a/c or heating unit, so not sure if...
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This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC