Stayed here for 4 nights for the Berlin Marathon. The hotel is a nice mix of antique and modern, and the location is great. They have a secure parking facility, and the U-bahn and S-bahn train stations are a block away. S-bahn from here take about 10 minutes to get to Unter der Linden, Brandenburg Gate, the Reichstag, and the main downtown shopping district. If you want to go across town to Charlottenburg, the Zoo, etc. it takes about another 20 minutes with train changes.
It is also only a ten minute walk from Museum Island, as well as 2 streets (Tor strasse and ??) that were full of restaurants and bars that stayed open with great nightlife until dawn.

My husband and I stayed for three nights in September 2010. The gentleman at the front desk was great helping us navigate the city by public transportation. Our room was small but nice - a little out of the way - but we didn't mind and welcomed the exercise by walking.

overall I enjoyed my stay here. quiet, close to our office, peaceful and chilled out reception. decent but not great value for Berlin, but the breakfast was very good. do spend a few minutes in the garden if you have time, for some reflection/tranquility. I had a room in the garden, which is a modern building so less charm than main building, but still quite nice. one note though - hotel was cash only, so I ended up needing to have 400 in cash to pay for 3 nights stay there! so remember to carry an extra wad of cash if you stay there. do consider dinner at their sister hotel round the corner - pretty cool vibe and good value dinner.

This hotel is a little farther out of the "main" area of Berlin, but is a pleasant walk into the main tourist attractions. It's clean, the staff are friendly and happy to help. The one issue we had was no AC. They provided us with a fan - but had to use the one they had set up in the main lobby! The garden in the back is beautiful - perfect place to have breakfast and start the day. They also have a computer in the lobby for free internet. I highly recommend this hotel.