I pretty much agree with the nice reviews below. It's a modern(-ish) and clean place, close to a lot of interesting places, and pretty much in the middle of everything (though I'd probably rather stay in Kreuzberg, Prenzlauer Berg or even Friedrichshain).

Anyway, I just wanted to register one very large complaint:
Nowhere in the hotel - not the rooms, not the lobby, not the restaurant - is it possible to get a cup of coffee outside of breakfast opening hours!

The minibar was ridiculously overstuffed, but no coffee. And the receptionist, nice and friendly as she was, didn't know where to get a cup nearby. Luckily I found one (1!) cafe that was open until 9 pm - all the other, Starbucks, Einstein, etc. closed earlier) - so I got my fix, but it's very close to being a dealbreaker when you're on a business trip and need to work in the evenings.

Oh, and by the way - the paid wifi is pretty expensive and only has 30 or 120 minute deals. I really, really hate that - I would rather pay an extra 10-20 Euro per night and have free wifi and not have to bother with paying and registering credit cards and so on. Will they ever learn?

Excellend spot in the midle of Mitte, spacious rooms, cleanness, good personnel,
good breakfast
The only bad thing was that they asked us to pay in advance!

We have stayed at this great hotel before, and if in berlin we will always come here. It has a great location, just a 5 min walk to check point charlie, 5 min walk to underground, a good base for exploring Berlin. The hotel itself is quite small but that suits us, rooms clean and fair size. Nice breakfast room, serving usual continental breakfasts, all very tasty. our breakfast was included in the price of the room, I think it is better to deal direct with the hotel. Joined to the hotel is a lowenbrau beerkeller, they have a good menu at reasonable prices, please note however there is more choice on the german menu, than the english this is due to menu changes, the staff are friendly and very helpful. And are happy to go through the menu with you. Would I come back to this hotel again - you bet. I recomend a visti to the Ka Da We department store, especially the 6th floor a must for foodies, plenty of food options. If in Alexanderplatz have a drink by the river on the outside terrace of the radison, go inside and see the giant fish tank in reception, look up it is not at eye level. Take a boat trip from here at only 7 euros it was very good value, please note the guide may only speak german, this didn't bother us, had a nice relaxing boat ride. weather was fantastic, take sun cream.

we stayed there 2 nights.
the location is simply perfect, just 1 building (the hilton hotel) far from gendarmenmarkt.
bus M48 close to the hotel and metro stop Stadtmitte 1 minute far.
checkpoint charlie is at 5 min walking., the same for friedrichstrasse and unter den linden.

the room was perfectly clean, quite big, with enough space for the luggage. hot water without problem.
we payed 93 euro for a double, with private bathroom and buffet breakfast included.

very kind and smiling staff, at the reception and in the breakfast room too.

breakfast room is lovely! and the same is for the restaurant "lowenbrau" that is part of the hotel, but open to everybody.

i'd come back to this hotel for sure, and i'll tell to all my friends.