My wife and I stayed here on the second leg of our honeymoon and we thought that of the six hotels we stayed at during the entire trip, this one was one of the best.
The room was great with a large bed and a great bathroom. The hotel staff was very helpful in helping us find our way downtown and to locations all over Munich. They also have a great breakfast buffet and their restaurant was very nice as well.
Despite how far away this hotel is from downtown Munich, we will only stay here any time we come back to Munich. This was a great hotel and we highly recommend it.

We stayed at the Prinzregent for one night during a tour of Bavaria in August 2011 and our overall impression was very favourable
Liked
1. The Hotel is modern, elegant and clean with a Bavarian style interior
2. The Rooms, Reception Area & Dining Area are all very well presented
3. The Hotel has a lovely Garden Area for eating and drinking
4. All the staff are friendly and helpful
5. There are nearby train links to Munich (approx 3 mins walk away to the train station and 6 stops to Munich)
6. If you "go around the block" at the back of the hotel you will find a lovely area with Church, Italian Restuarant and a few Bavarian style houses
7. The Breakfast Buffet was exceptional with a wide variety of choices from cereals, cold meats, various cheeses, biscuits, cakes and pastry to hot food such as sausages, bacon & egg
Disliked
1. There is not much to do of an evening. There is only an Italian and Greek Restuarant near the hotel and a cafe opposite and the hotel does not provide any evening entertainment thou there is a bar and the garden area is open of an evening. As we were only here for one night it didn't really bother us too much.
2. The Restuarant prices were slightly expensive. We had a meal consisting of lamb, pototaoes and veg that came to just over 20 Euros. Whilst the lamb and accompaning sauce was very nice, the potatoes and veg were very under cooked
3. We could only find one channel on the TV in our room that was in English (CNN)

We only stayed there for one night on our way from Rothenburg to Fussen, but the hotel was great. Very convenient, comfortable rooms, nice bar and very good food at the restaurant/bar. We rolled in in the late afternoon after a long day and had a blast at the bar. Didn't seem much of Munich, but we very much enjoyed our night at this hotel.

Although this hotel appears to be a bit out of town, it's located within 1/2 mile of the Messe and only 400 meters to a S-bahn stop that gets you into the city center in 15 minutes. Good size rooms - very quiet and relaxing. We enjoyed a wonderful gourmet dinner the first night after driving through Bavaria and checking in late afternoon. Breakfast was great - the omelets to order were the best we have every had! Nice bar and even a beer garden to relax outside. A definate place for a return visit to Munich!