Hotel Saint Roch meets two out of our three traveler's CCC's criteria: convenient and clean. It falls short of comfort, albeit in all other respects it met our needs, and the rest of Avignon provides charm and character in spades to make up for a stay where a bit of discomfort wasn't such a drama.
As a receptionist, our host has a definite future in the public service such was the seriousness with which he takes himself. Not that there was anything wrong with his service - it was more the formality and sternness of his delivery. He did offer plenty of useful advice, for which we were very grateful, though his answer was always the same - a map showing where the Avignon Office de Tourisme was located. The staff there are wonderful and certainly know how to market their city to both tourists and travelers alike.
We liked the convenience of Hotel Saint Roch - it is no more than a 10 minute stroll to any where more interesting than what it offers, and it does a lovely breakfast in the court yard garden. A setting we also used to good effect for a self-catered dinner of fresh local fare. The rooms are spacious however comfortable is not a word that comes to mind to describe them. It does however offer value for money if you're looking for a convenient location. Parking could be a problem - it's what ever you can grab in the street.

We just stayed for 2 nights and was good for that...bed was way to hard!. Hotel is quite decent & in a good location, we had to catch a train from Avignon centre and was easy to walk to. Would recommend for short stay

Good location, 10 minute walk into the centre of avaignon, a lovely walled town.
Nice large rooms, but beds could be more comfortable, service could be a bit more welcoming, and the air conditioners made horrible noises during the night.
The hotel did had a lovely walled garden where breakfast was served, and it was in a quiet street.

Nice hotel - with efficient staff.

Breakfast in the garden was delightful.