Le Clos d'Amboise is in a wonderful location, withing walking distance to Clos Luce (Da Vinci's house) and many places to eat. Free car parking is available, and if the on-site parking - which can get a bit cramped and awkward to manouver in - is full, there is free parking about 50m up the road. It might depend on when you go how much competition there is for the free public parking!
I had a beautiful room, comfortable bed, big modern bathroom, overlooking the garden in the annexe (there are two parts to Le Clos Amboise). It was quiet, save for the wind in the trees and the occasional crunch of feet on gravel paths. The windows in the bathroom were screened only by those thin internal curtains, which is a bit odd, esp when you are in the shower at night - I just hung a towel up when I was showering, as I was not sure if the curtains would offer sufficient privacy!
The breakfast was very good, with a nice variety on offer, although be aware it is an extra charge. Free WiFi in all areas, and a beautifully furnished place to sit and read papers at the end of the day. There is a pool, but I didn't use it, as the weather was a bit cool by October.
Amboise is a great base for exploring chateaux, as some are 50km east and some 50km west of Amboise, which is central to all. I would absolutely NOT stay in Tours, its too big and if you have a car (which in my view is much better for exploring chateaux than going on a tour), I would not want to navigate in and out of there unless you are very familiar with the city.
Minor thing, more for traveller's advice than a criticism of the hotel - the sign identifying Le Clos D'amboise on the road has the world 'hotel' in very large letters, but the crucial words 'Clos D'amboise' are small and hard to read for those trying to find the place for the first time. The sign is fine if you are walking, but tricky when driving, as it is a one way road and if you have traffic up behind you, you can overshoot the driveway and have to do a lap out and around (5 mins) to get back.
This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC